AICAR 10mg (50 Tablets)

**AICAR 10mg**, also known as Acadesine or AICA Ribonucleotide, is a powerful research compound that activates AMPK (AMP-activated protein kinase). Researchers widely use it to explore metabolic regulation, energy balance, and endurance pathways. Each bottle contains **50 tablets** of **10mg AICAR**, delivering a total of 500mg for various laboratory protocols.

This compound mimics low-energy states in cells, making it an important tool in metabolic and exercise-related studies.

AICAR is taken up by cells and converted to ZMP, an AMP analog. This directly activates AMPK, a key energy sensor in the body. Activated AMPK promotes fatty acid oxidation, glucose uptake, and mitochondrial biogenesis.

It influences multiple pathways including PGC-1α, which supports mitochondrial function. Researchers value AICAR for its ability to simulate exercise effects at the cellular level without physical activity.

The compound’s action on AMPK helps regulate energy homeostasis. This makes it suitable for in-depth studies on metabolism and cellular stress responses.

 Key Research Applications

Scientists investigate AICAR (10MG) (50 TABLETS) across many areas. Primary focus includes fat metabolism and lipid oxidation. It is also used in endurance and muscle adaptation research.

Glucose regulation and insulin sensitivity form another major application. Researchers explore its role in obesity, diabetes, and metabolic disorder models. Muscle preservation during various conditions receives attention too.

Additional studies examine neuroprotective effects and brain aging models. Some protocols investigate combination effects with other research compounds. All applications remain strictly in controlled laboratory environments.

 Potential Outcomes in Preclinical Studies

Preclinical research highlights several interesting findings. In one landmark mouse study, AICAR treatment increased running endurance by up to 44% in sedentary animals. This occurred through enhanced oxidative metabolism and slow-twitch muscle fiber adaptations.

Studies show improved fat oxidation and reduced adiposity in animal models. Chronic AICAR administration can remodel white adipose tissue metabolism and increase mitochondrial density.

Glucose uptake improves in various tissues, sometimes independent of insulin. Researchers observe better mitochondrial function and biogenesis in muscle cells. These outcomes support its use as an “exercise mimetic” in lab settings.

Bone and muscle wasting models also benefit from investigation with AICAR. Some research explores its effects on hippocampal function and memory in aging models. All results are from animal or in-vitro studies only.

**Important Note**: These findings do not translate to human applications. AICAR remains an experimental research tool.

 History and Development of AICAR (10MG) (50 TABLETS)

AICAR, or Acadesine, was originally developed as a potential therapeutic for cardiac ischemia and reperfusion injury during surgery. It reached Phase III clinical trials for preventing complications in coronary artery bypass graft procedures.

Development for cardiac use was later discontinued due to insufficient efficacy. Attention then shifted toward its metabolic properties, especially after animal studies demonstrated strong endurance-enhancing effects.

Since 2009, the World Anti-Doping Agency (WADA) has banned AICAR as a metabolic modulator. It is prohibited in competitive sports due to its performance-enhancing potential in research models.

This history provides rich context for scientific analysis of AMPK activators and their broader implications in pharmacology.

### Product Specifications – AICAR 10mg

– **Active Compound**: AICAR (Acadesine / AICA Ribonucleotide)

– **Dosage per Tablet**: 10mg

– **Tablet Count**: 50 tablets

– **Total Content**: 500mg

– **Form**: Compressed research tablets for precise dosing

– **Purity**: High-purity research grade

– **Storage**: Cool, dry place away from direct light and moisture

– **Shelf Life**: Stable when stored properly

– **Intended Use**: Laboratory research and analytical purposes only

The tablet form offers convenience and accuracy for experimental setups. It reduces handling variability compared to powder or liquid forms.

 Suggested Research Use (Lab Protocols Only)

Research protocols vary widely depending on study goals. Common doses in animal models range significantly higher per body weight, while cell studies use micromolar concentrations.

For tablet-based research, scientists often reference 5–20mg ranges in specific designs, but exact parameters must come from published literature. Duration can span days to weeks in chronic studies.

Researchers should always consult primary scientific papers and adhere to institutional ethical guidelines. Factors like model type, duration, and combination therapies influence outcomes.

Careful documentation and controls ensure reproducible results in laboratory experiments.

 Comprehensive Safety Profile and Research Considerations

In preclinical models, AICAR is generally studied at controlled doses. Potential effects include metabolic shifts, changes in cell growth patterns, and alterations in energy substrate utilization.

Some studies note risks of hypoglycemia due to enhanced glucose uptake. High doses in certain models may lead to other metabolic imbalances. Human clinical data from earlier trials showed acceptable short-term safety at specific intravenous doses, but this does not apply to research chemicals.

**Critical Disclaimer**: **AICAR 10mg** is sold **strictly for laboratory and scientific research only**. It is **not for human consumption**, therapeutic use, diagnostic purposes, or any form of self-experimentation. Significant health risks may exist outside approved research facilities.

This compound is banned by WADA and prohibited in sports. Researchers must comply with all local, national, and institutional regulations. Proper PPE and safety protocols are mandatory during handling.

 Broader Scientific Context and Future Research Directions

AICAR serves as a valuable pharmacological tool for understanding AMPK signaling. AMPK acts as a master regulator of cellular energy, influencing everything from metabolism to inflammation and longevity pathways.

Comparisons with exercise and other activators help scientists map molecular adaptations. Research continues into its potential in age-related conditions, neurodegenerative models, and metabolic syndromes.

Future studies may explore more selective AMPK activators or combination approaches. Neuroprotective and anti-aging angles are gaining interest in laboratory settings. All work advances fundamental knowledge in biochemistry and physiology.

 Why Choose This AICAR (10MG) (50 TABLETS) Formulation for Your Research?

– Precise 10mg dosing supports reproducible experiments

– 50-tablet supply fits multi-week or multi-subject protocols

– High-purity research grade material ensures reliable data

– Convenient tablet form simplifies laboratory handling

– Professional packaging maintains compound stability

This formulation meets the needs of serious research environments focused on metabolic and endurance studies.

 Frequently Asked Questions About AICAR (10MG) (50 TABLETS)

**Q1: What is AICAR 10mg?**

**A:** AICAR 10mg is an AMPK activator used in laboratory research for metabolic regulation, endurance, and energy homeostasis studies. Each bottle contains 50 tablets.

**Q2: What does AICAR research focus on?**

**A:** Researchers study **AICAR 10mg** for fat metabolism, glucose uptake, endurance enhancement, mitochondrial function, and exercise mimetic effects in preclinical models.

**Q3: How many tablets are in one bottle of AICAR 10mg?**

**A:** One bottle contains **50 tablets** of **10mg AICAR**, providing a total of 500mg for research use.

**Q4: Is AICAR legal for research?**

**A:** It is legal for legitimate laboratory research in many jurisdictions. It is not approved for human use and is banned in sports. Always check local regulations.

**Q5: What is the typical research dosage for AICAR?**

**A:** Dosages vary widely by model and protocol. Researchers must follow published scientific literature for their specific experimental design.

**Q6: Is AICAR safe for human use?**

**A:** **No**. This product is **not for human consumption**. It is for laboratory research only and may carry metabolic and other risks.

**Q7: How should I store AICAR 10mg tablets?**

**A:** Store in a cool, dry place away from direct sunlight and moisture to preserve stability.

**Q8: What are notable findings in AICAR studies?**

**A:** Key observations include up to 44% endurance increase in sedentary animal models, enhanced fat oxidation, and improved mitochondrial function.

**Q9: Can AICAR be used for performance enhancement?**

**A:** No. It is intended **strictly for laboratory research** only and is prohibited in competitive sports.

**Q10: What is the purity of your AICAR 10mg?**

**A:** Our AICAR is high-purity research grade, suitable for analytical chemistry and advanced experimental research.